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Elevated T-cell exhaustion and urinary tumor DNA levels are associated with BCG failure in patients with non-muscle invasive bladder cancer

2022-03-23

Abstract excerpt

<h4>Background</h4> The functional status of immune cells within the tumor microenvironment and tumor characteristics may explain Bacillus Calmette-Guérin (BCG)-failure in high-risk non-muscle invasive bladder cancer (NMIBC). <h4>Objective</h4> To characterize molecular correlates of BCG-failure using a multiomics approach. <h4>Design, Setting, and Participants</h4> BCG-treated NMIBC patients (n=156) were included...

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Literature Corpus work
8f8af46b-0fe6-5bc3-bf25-eb7f5955ba0c
DOI
10.1101/2022.03.23.22272806
Open publication

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Elevated T-cell exhaustion and urinary tumor DNA levels are associated with BCG failure in patients with non-muscle invasive bladder cancerDOI 10.1101/2022.03.23.22272806
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