Article
Comprehensive genome-wide association study into multiple recurrence and progression risk in non-muscle invasive bladder cancer.
Cancer genetics - 1 Sept 2026
Hof Jasper P, Galesloot Tessel E, Aben Katja K H, Bryan Richard T, Catto James W F, Cheng Kar K, Conroy Samantha, Fleshner Neil E, van der Heijden Antoine G, James Nicholas D, Mengual Lourdes, Uunk Florine M, Verhaegh Gerald, Vrieling Alina, Zeegers Maurice P, Kiemeney Lambertus A L M, Vermeulen Sita H
Abstract excerpt
BACKGROUND: Patients with non-muscle invasive bladder cancer (NMIBC) frequently experience recurrence and may progress to muscle-invasive disease. Although several common germline variants associated with bladder cancer risk have been identified, their prognostic value in NMIBC remains unclear. We performed an updated genome-wide association study (GWAS), incorporating additional cohorts and analysing multiple...
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