Article

RBMX enables productive RNA processing of ultra-long exons important for genome stability

2020-10-09

Abstract excerpt

Previously we showed that the germline-specific RNA binding protein RBMXL2 is essential for male meiosis where it represses cryptic splicing patterns (1). Here we find that its ubiquitously expressed paralog RBMX helps underpin human genome stability by preventing non-productive splicing. In particular, RBMX blocks selection of aberrant splice and polyadenylation sites within some ultra-long exons that would inter...

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Literature Corpus work: 4f072662-a608-5029-aca6-fcf3ff8520af
DOI: 10.1101/2020.10.09.333039

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