Article
RBM5 is a male germ cell splicing factor and is required for spermatid differentiation and male fertility.
PLoS genetics - 1 Jan 2013
O'Bryan Moira K, Clark Brett J, McLaughlin Eileen A, D'Sylva Rebecca J, O'Donnell Liza, Wilce Jacqueline A, Sutherland Jessie, O'Connor Anne E, Whittle Belinda, Goodnow Christopher C, Ormandy Christopher J, Jamsai Duangporn
Abstract excerpt
Alternative splicing of precursor messenger RNA (pre-mRNA) is common in mammalian cells and enables the production of multiple gene products from a single gene, thus increasing transcriptome and proteome diversity. Disturbance of splicing regulation is associated with many human diseases; however, key splicing factors that control tissue-specific alternative splicing remain largely undefined. In an unbiased...
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