Article

HIV superinfection reveals sequential reservoir reactivation and immune-driven rebound dynamics

2026-03-20

Abstract excerpt

<h4>ABSTRACT</h4> Superinfection, where a person with HIV acquires a second phylogenetically distinct strain, provides an opportunity to study reservoir evolutionary dynamics because the two strains can be tracked over time. We here characterize such a case that originally went undetected by clinical monitoring. The participant, who expressed the protective HLA-B*57:03 allele, initially controlled his subtype B i...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 4f05e344-aa8e-56df-a7b4-f31a9767a601
DOI: 10.64898/2026.03.18.712773

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

HIV superinfection reveals sequential reservoir reactivation and immune-driven rebound dynamicsDOI 10.64898/2026.03.18.712773Read

HIV SuperinfectionSemantic proximity Read

In-Depth Analysis of a Heterosexually Acquired Human Immunodeficiency Virus Type 1 Superinfection: Evolution, Temporal Fluctuation, and Intercompartment Dynamics from the Seronegative Window Period through 30 Months PostinfectionSemantic proximity Read

HIV Rebound Is Predominantly Fueled by Genetically Identical Viral Expansions from Diverse ReservoirsSemantic proximity Read

Extensive characterization of HIV-1 reservoirs reveals links to plasma viremia before and during analytical treatment interruptionSemantic proximity Read

Frequency and implications of HIV superinfection.Semantic proximity Read

Origin of Rebound Plasma HIV Includes Cells with Identical Proviruses That Are Transcriptionally Active before Stopping of Antiretroviral Therapy.Semantic proximity Read

Dynamics of HIV DNA reservoir seeding in a cohort of superinfected Kenyan womenSemantic proximity Read

Immune-driven recombination and loss of control after HIV superinfection.Semantic proximity Read

Human immunodeficiency virus type 1 clade B superinfection: evidence for differential immune containment of distinct clade B strains.Semantic proximity Read

Recurrent mutations drive rapid HIV escape from two broadly neutralizing antibodies <i>in vivo</i>Semantic proximity Read

HIV-1 Superinfection Resembles Primary Infection.Semantic proximity Read

Plasma neutralizing antibodies in an infant with interclade HIV-1 superinfection preferentially neutralize superinfecting HIV-1 strainsSemantic proximity Read