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Article

Dynamics of HIV DNA reservoir seeding in a cohort of superinfected Kenyan women

5 Feb 2020

Abstract excerpt

A reservoir of HIV-infected cells that persists despite suppressive antiretroviral therapy (ART) is the source of viral rebound upon ART cessation and the major barrier to a cure. Understanding reservoir seeding dynamics will help identify the best timing for HIV cure strategies. Here we characterize reservoir seeding using longitudinal samples from before and after ART initiation in individuals who sequentially...

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PMID: 32023326
DOI: 10.1371/journal.ppat.1008286

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