Article
Hallmarks of frailty and osteosarcopenia in prematurely aged PolgA <sup>D257A/D257A</sup> mice
2019-09-05
Abstract excerpt
<h4>Background</h4> Frailty is a geriatric syndrome characterized by increased susceptibility to adverse health outcomes. One major determinant thereof is the gradual weakening of the musculoskeletal system and the associated osteosarcopenia. To improve our understanding of the underlying pathophysiology and, more importantly, to test potential interventions aimed at counteracting frailty suitable animal models a...
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Identifiers and source
- Literature Corpus work
- 4eb71654-7a7d-5cd1-b1a6-1c3e963b8bea
- DOI
- 10.1101/758243