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Article

Assessing frailty in aged zebrafish using a quick pseudo-frailty index.

Biology open - 15 Apr 2026

Hyde Anne Cathrine, Ellis Pamela, El-Khamisy Sherif, Allen Claire, Henriques Catarina M, van Eeden Fredericus J

Abstract excerpt

While biomedical advancements have significantly extended human longevity, increased lifespan is frequently decoupled from healthspan, as these additional years are often accompanied by frailty and chronic morbidity. Frailty is characterised by a multisystem decline in physiological reserve and renders individuals disproportionately vulnerable to adverse outcomes - including mortality - when faced with health...

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PMID: 41867115
DOI: 10.1242/bio.062345
PMCID: PMC13148474

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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