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Article

Frailty in rodents: Models, underlying mechanisms, and management.

Ageing research reviews - 1 Aug 2022

Liu Pan, Li Yun, Ma Lina

Abstract excerpt

Frailty is a clinical geriatric syndrome characterized by decreased multisystem function and increased vulnerability to adverse outcomes. Although numerous studies have been conducted on frailty, the underlying mechanisms and management strategies remain unclear. As rodents share homology with humans, they are used extensively as animal models to study human diseases. Rodent frailty models can be classified...

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PMID: 35660004
DOI: 10.1016/j.arr.2022.101659

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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