Article
Phenotypic Frailty Assessment in SAMP8 Mice: Sex Differences and Potential Role of miRNAs as Peripheral Biomarkers.
The journals of gerontology. Series A, Biological sciences and medical sciences - 28 Oct 2023
Musazzi Laura, Carini Giulia, Barbieri Silvia S, Maggi Stefania, Veronese Nicola, Popoli Maurizio, Barbon Alessandro, Ieraci Alessandro
Abstract excerpt
Frailty is a geriatric syndrome characterized by age-related decline in physiological reserves and functions in multiple organ systems, including the musculoskeletal, neuroendocrine/metabolic, and immune systems. Animal models are essential to study the biological basis of aging and potential ways to delay the onset of age-related phenotypes. Unfortunately, validated animal models of frailty are still lacking in...
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