Article

The Investigation of Genetic and Clinical Features in Patients with Hereditary Spastic Paraplegia in Central-Southern China

2020-07-21

Abstract excerpt

<title>Abstract</title> <p><bold>Objective </bold>Hereditary spastic paraplegias (HSPs) are a clinically and genetically heterogeneous group of neurodegenerative disorders. We describe the genetic and clinical features of a cohort of five HSP families from central-southern China. <bold>Methods </bold>Using targeted exome-sequencing technology, we investigated the genetic and clinical features in five HSP families...

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Literature Corpus work: 4eaec949-2800-595d-b7c2-3154f941fddf
DOI: 10.21203/rs.3.rs-43715/v1

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