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The investigation of genetic and clinical features in patients with hereditary spastic paraplegia in central-Southern China.

Molecular genetics & genomic medicine - 1 May 2021

Wang Chen, Zhang Yun-Jian, Xu Ci-Hao, Li De, Liu Zhi-Jun, Wu Yan

Abstract excerpt

OBJECTIVE: Hereditary spastic paraplegias (HSP) is a clinically and genetically heterogeneous group of neurodegenerative disorders. We describe the genetic and clinical features of a cohort of five HSP families from central-southern China. METHODS: Using targeted exome-sequencing technology, we investigated the genetic and clinical features in five HSP families. We reviewed the clinical histories of these...

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Identifiers

PMID: 33638609
DOI: 10.1002/mgg3.1627
PMCID: PMC8172193

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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