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Novel SPG 11 Mutations in Hereditary Spastic Paraplegia With Thin Corpus Callosum in a Chinese Family.

The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques - 1 Nov 2016

Tian Xiaojie, Wang Min, Zhang Kaiyuan, Zhang Xinqing

Abstract excerpt

BACKGROUND: Hereditary spastic paraplegia (HSP) is a neurodegenerative disease that is characterized by progressive weakness and spasticity of the lower extremities; HSP can present as complicated forms with additional neurological signs. More than 70 disease loci have been described with different modes of inheritance. METHODS: In this study, nine subjects from a Chinese family that included two individuals...

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PMID: 27018819
DOI: 10.1017/cjn.2016.17

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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