Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Clinical spectrum and genetic landscape for hereditary spastic paraplegias in China.

Molecular neurodegeneration - 6 Jul 2018

Dong En-Lin, Wang Chong, Wu Shuang, Lu Ying-Qian, Lin Xiao-Hong, Su Hui-Zhen, Zhao Miao, He Jin, Ma Li-Xiang, Wang Ning, Chen Wan-Jin, Lin Xiang

Abstract excerpt

BACKGROUND: Hereditary spastic paraplegias (HSP) is a heterogeneous group of rare neurodegenerative disorders affecting the corticospinal tracts. To date, more than 78 HSP loci have been mapped to cause HSP. However, both the clinical and mutational spectrum of Chinese patients with HSP remained unclear. In this study, we aim to perform a comprehensive analysis of clinical phenotypes and genetic distributions in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Asian People
Share to Child

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Child, Preschool

Share to Infant

Share to Infant, Newborn

Share to Spastic Paraplegia, Hereditary

Share to Young Adult

Source

Open in PubMed Open full text

Identifiers

PMID: 29980238
DOI: 10.1186/s13024-018-0269-1
PMCID: PMC6035405

Genes

SPG11
LAMP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Clinical spectrum and genetic landscape for hereditary spastic paraplegias in China.PMID 29980238Read ↗

Clinical features and genetic spectrum in Chinese patients with recessive hereditary spastic paraplegiaSemantic proximity Read ↗

The investigation of genetic and clinical features in patients with hereditary spastic paraplegia in central-Southern China.Semantic proximity Read ↗

Mutation and clinical characteristics of autosomal-dominant hereditary spastic paraplegias in China.Semantic proximity Read ↗

Hereditary spastic paraplegia: new insights into clinical variability and spasticity-ataxia phenotype, and novel mutations.Semantic proximity Read ↗

Chinese patients with hereditary spastic paraplegias (HSPs): a protocol for a hospital-based cohort study.Semantic proximity Read ↗

Expansion of the mutation and phenotypic spectrum of hereditary spastic paraplegia.Semantic proximity Read ↗

Insights into Clinical, Genetic, and Pathological Aspects of Hereditary Spastic Paraplegias: A Comprehensive OverviewSemantic proximity Read ↗

The emerging genetic diversity of hereditary spastic paraplegia in Korean patients.Semantic proximity Read ↗

JASPAC: Japan Spastic Paraplegia Research ConsortiumSemantic proximity Read ↗

A novel SPAST gene mutation identified in a Chinese family with hereditary spastic paraplegia.Semantic proximity Read ↗

Genetic landscape of hereditary spastic paraplegias in the Korean population.Semantic proximity Read ↗

Clinical and genetic spectrum of hereditary spastic paraplegia in Chinese children.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.