Article

Clinical characteristics and gene mutation analysis of a family with hereditary spastic paraplegia type 11

2022-11-29

Abstract excerpt

<h4>Background: </h4> ： Autosomal recessive spastic paraplegia with thinning of corpus callosum (ARHSP-TCC) is a complex hereditary spastic paraplegia. Spastic Paraplegia gene 11(SPG11) is the most common ARHSP-TCC. The study of SPG11 in China is small in scale, and only a few gene mutations have been reported . Case Presentation: We reported a family with ARHSP-TCC. The proband presented spastic gait and cogniti...

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Literature Corpus work: 1cafdd6b-84ea-5e88-9efa-d195bf72b846
DOI: 10.21203/rs.3.rs-2269224/v1

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