Article

Aging trajectories of memory CD8 <sup>+</sup> T cells differ by their antigen specificity

2024-07-29

Abstract excerpt

Memory T cells are a highly dynamic and heterogeneous population that is maintained by cytokine-driven homeostatic proliferation interspersed with episodes of antigen-mediated expansion and contraction which affect their functional state and their durability. This heterogeneity complicates studies on the impact of aging on global human memory cells, specifically, it is unclear how aging drives memory T cell dysfun...

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Literature Corpus work: 4ea44259-a1c3-5a08-9f25-113161aa919f
DOI: 10.1101/2024.07.26.605197

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