Hiding in Plain Sight: Virtually Unrecognizable Memory Phenotype CD8+ T cells

doi:10.3390/ijms21228626

Article

Hiding in Plain Sight: Virtually Unrecognizable Memory Phenotype CD8+ T cells

16 Nov 2020

Abstract excerpt

Virtual memory T (TVM) cells are a recently described population of conventional CD8+ T cells that, in spite of their antigen inexperience, express markers of T cell activation. TVM cells exhibit rapid responsiveness to both antigen-specific and innate stimuli in youth but acquire intrinsic antigen-specific response defects in the elderly. In this article, we review how the identification of TVM cells...

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.