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Conversational Artificial Intelligence-Enabled Precision Oncology Reveals Context-Specific TGFβ and JAK/STAT Alterations in Pancreatic Cancer

2026-06-12

Abstract excerpt

<h4>Background</h4> Pancreatic ductal adenocarcinoma (PDAC) is characterized by extensive molecular complexity, profound stromal remodeling, and limited responsiveness to systemic therapies. Although gemcitabine-based regimens remain widely utilized, the molecular pathways that influence treatment-associated biological variation are incompletely understood. The TGFβ and JAK/STAT signaling networks are recognized...

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Literature Corpus work
4ea3cc92-bf33-552c-b722-afdaabf958c3
DOI
10.64898/2026.06.10.26355398
Open publication

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