Article

A Conversational Artificial Intelligence Framework for Comparative Pathway-Level Profiling of Sézary Syndrome and Primary Cutaneous CD8 <sup>+</sup> Aggressive Epidermotropic Cytotoxic T-Cell Lymphoma (PCAECTCL)

2026-04-17

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Sézary syndrome (SS) is an aggressive leukemic variant of cutaneous T-cell lymphoma (CTCL) with distinct clinical and biological features compared to rarer entities such as primary cutaneous CD8⁺ aggressive epidermotropic cytotoxic T-cell lymphoma (PCAECTCL). Although recurrent genomic alterations in CTCL have been described, comparative analyses at the pathway level across...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 2ba14541-1c08-5746-a320-7887dba89fc9
DOI: 10.64898/2026.04.15.26350992

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

A Conversational Artificial Intelligence Framework for Comparative Pathway-Level Profiling of Sézary Syndrome and Primary Cutaneous CD8 <sup>+</sup> Aggressive Epidermotropic Cytotoxic T-Cell Lymphoma (PCAECTCL)DOI 10.64898/2026.04.15.26350992Read

Conversational Artificial Intelligence-Enabled Molecular Characterization of Sézary Syndrome Reveals Distinct Pathway-Level Alterations Compared with Non-Sézary Cutaneous T-Cell LymphomaSemantic proximity Read

Conversational Artificial Intelligence Agents-Enabled Dissection of RTK-RAS and MAPK Pathway Dependencies in Gemcitabine-Treated Pancreatic Ductal Adenocarcinoma (PDAC)Semantic proximity Read

Deciphering RTK-RAS and MAPK Pathway Dependencies in Gemcitabine-Treated Pancreatic Ductal Adenocarcinoma Through Conversational Artificial Intelligence.Semantic proximity Read

Conversational Artificial Intelligence-Enabled Precision Oncology Reveals Context-Specific TGFβ and JAK/STAT Alterations in Pancreatic CancerSemantic proximity Read

Deregulation of JAK2 signaling underlies primary cutaneous CD8+ aggressive epidermotropic cytotoxic T-cell lymphomaSemantic proximity Read

Conversational Artificial Intelligence-Based Integration of Clinical and Genomic Data Identifies MAPK Alterations in Colorectal CancerSemantic proximity Read

Artificial intelligence for precision oncology: AI-HOPE-MAPK uncovers clinically actionable MAPK alterations in colorectal cancerSemantic proximity Read

Comprehensive and Integrated Genomic Characterization of Human Immunome in CancerSemantic proximity Read

From Mutation to Prognosis: AI-HOPE-PI3K Enables Artificial Intelligence-Agent Driven Integration of PI3K Pathway Data in Colorectal Cancer Precision MedicineSemantic proximity Read

Integrated Genomic Characterization of the Human Immunome in Cancer.Semantic proximity Read

IMMUNIA: A Multi-LLM Reasoning Agent for Immunoregulatory Surfaceome DiscoverySemantic proximity Read

Artificial Intelligence-Enabled Integration Suggests TP53 Pathway Alterations as Prognostic Biomarkers in Populations with Disproportionate Health Burdens.Semantic proximity Read