Article

Distinct gene programs underpinning 'disease tolerance' and 'resistance' in influenza virus infection

2022-03-22

Abstract excerpt

When challenged with an invading pathogen, the host defense response is engaged to eliminate the pathogen (resistance) and to maintain health in the presence of the pathogen (disease tolerance). However, the identification of distinct molecular programs underpinning disease tolerance and resistance remained obscure. We exploited transcriptional and physiological monitoring across 33 mouse strains, during in vivo i...

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Literature Corpus work: 5a1a6078-6ea2-507e-b3d6-857242360be8
DOI: 10.1101/2022.03.22.485254

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