Article

Metabolomic and lipidomic signatures in autosomal dominant and late-onset Alzheimer disease brains

2021-11-05

Abstract excerpt

The identification of multiple genetic risk factors for Alzheimer Disease (AD) provides evidence to support that many pathways contribute to AD onset and progression. However, the metabolomic and lipidomic profiles in carriers of distinct genetic risk factors are not fully understood. The metabolome can provide a direct image of dysregulated pathways in the brain, including information on treatment targets. In thi...

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Literature Corpus work: 4e157dbf-afe0-5659-8995-35a5a9597a46
DOI: 10.1101/2021.11.04.21265941

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