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A seven-year longitudinal study of the Alzheimer’s disease blood metabolome

2025-12-06

Abstract excerpt

Metabolic dysregulation is a hallmark of Alzheimer’s disease (AD), yet the temporal nature of metabolite–phenotype associations remains poorly understood. We systematically evaluated 506 serum metabolites across 4,063 longitudinal samples from 1,430 participants in the Alzheimer’s Disease Neuroimaging Initiative (ADNI), applying cross-sectional single-timepoint analyses, multi-timepoint meta-analysis, and time-int...

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Literature Corpus work
b05454df-df88-55b6-9707-3a9c66643e2f
DOI
10.64898/2025.12.05.25341709
Open publication

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A seven-year longitudinal study of the Alzheimer’s disease blood metabolomeDOI 10.64898/2025.12.05.25341709
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