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Integrative metabolomics‐genomics approach reveals key metabolic pathways and regulators of Alzheimer's disease

10 Nov 2021

Abstract excerpt

Metabolites, the biochemical products of the cellular process, can be used to measure alterations in biochemical pathways related to the pathogenesis of Alzheimer's disease (AD). However, the relationships between systemic abnormalities in metabolism and the pathogenesis of AD are poorly understood. In this study, we aim to identify AD-specific metabolomic changes and their potential upstream genetic and...

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PMID: 34757660
DOI: 10.1002/alz.12468

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