Article

An HIV-Tat inducible mouse model system of childhood HIV-associated nephropathy

2020-05-08

Abstract excerpt

<h4>Background</h4> Modern antiretroviral therapies (ART) have decreased the prevalence of HIV-associated nephropathy (HIVAN). Nonetheless, we continue to see children and adolescents with HIVAN all over the world. Furthermore, once HIVAN is established in children, it is difficult to revert its long-term progression, and we need better animal models of childhood HIVAN to test new treatments. <h4>Objectives</h4>...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 4df8a289-61f8-5f13-b0cd-c26b32ba5684
DOI: 10.1101/2020.05.06.081851

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

An HIV-Tat inducible mouse model system of childhood HIV-associated nephropathyDOI 10.1101/2020.05.06.081851Read

Transgenic and Infectious Animal Models of HIV-Associated NephropathySemantic proximity Read

A novel HIV-1 transgenic rat model of childhood HIV-1–associated nephropathySemantic proximity Read

Pathogenesis of HIV-associated nephropathy in children and adolescents: taking a hard look 40 years later in the era of gene-environment interactions.Semantic proximity Read

Glomerulosclerosis and viral gene expression in HIV-transgenic mice: Role of nefSemantic proximity Read

HIV-associated nephropathy in transgenic mice expressing HIV-1 genesSemantic proximity Read

The molecular pathogenesis of HIV-1 associated nephropathy: recent advances.Semantic proximity Read

Recent Updates on Mouse Models for Human Immunodeficiency, Influenza, and Dengue Viral InfectionsSemantic proximity Read

Temporal Profile of the Renal Transcriptome of HIV-1 Transgenic Mice during Disease ProgressionSemantic proximity Read

Expression of HIV-1 genes in podocytes alone can lead to the full spectrum of HIV-1-associated nephropathy.Semantic proximity Read

Refinement of the HIVAN1 Susceptibility Locus on Chr. 3A1-A3 via Generation of Sub-Congenic Strains.Semantic proximity Read

Nephropathy in human immunodeficiency virus-1 transgenic mice is due to renal transgene expression.Semantic proximity Read

Exploiting rodent cell blocks for intrinsic resistance to HIV-1 gene expression in human T cellsSemantic proximity Read