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Recent Updates on Mouse Models for Human Immunodeficiency, Influenza, and Dengue Viral Infections

13 Mar 2019

Abstract excerpt

Well-developed mouse models are important for understanding the pathogenesis and progression of immunological response to viral infections in humans. Moreover, to test vaccines, anti-viral drugs and therapeutic agents, mouse models are fundamental for preclinical investigations. Human viruses, however, seldom infect mice due to differences in the cellular receptors used by the viruses for entry, as well as in the...

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PMID: 30871179
DOI: 10.3390/v11030252

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