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Temporal Profile of the Renal Transcriptome of HIV-1 Transgenic Mice during Disease Progression

25 Mar 2014

Abstract excerpt

Profiling of temporal changes of gene expression in the same kidney over the course of renal disease progression is challenging because repeat renal biopsies are rarely indicated in clinical practice. Here, we profiled the temporal change in renal transcriptome of HIV-1 transgenic mice (Tg26), an animal model for human HIV-associated nephropathy (HIVAN), and their littermates at three different time points (4, 8,...

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PMID: 24667548
DOI: 10.1371/journal.pone.0093019

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