Article
On the contribution of genetic heterogeneity to complex traits
2024-03-30
Abstract excerpt
Genetic heterogeneity, where different alleles or loci are responsible for similar phenotypes, reduces the power of genome-wide association studies and can cause misleading results. Although many striking examples have been identified, the general importance of genetic heterogeneity for complex traits is unclear. Here, we use a novel interpretative machine-learning approach to look for evidence of genetic heteroge...
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Identifiers and source
- Literature Corpus work
- 4df59232-b91b-565d-856f-3f94cdaac2f2
- DOI
- 10.1101/2024.03.27.586967