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Article

Finding genes that underlie complex traits.

Science (New York, N.Y.) - 20 Dec 2002

Glazier Anne M, Nadeau Joseph H, Aitman Timothy J

Abstract excerpt

Phenotypic variation among organisms is central to evolutionary adaptations underlying natural and artificial selection, and also determines individual susceptibility to common diseases. These types of complex traits pose special challenges for genetic analysis because of gene-gene and gene-environment interactions, genetic heterogeneity, low penetrance, and limited statistical power. Emerging genome resources...

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PMID: 12493905
DOI: 10.1126/science.1076641

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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