Article
The fog of genetics: Known unknowns and unknown unknowns in the genetics of complex traits and diseases
2019-02-18
Abstract excerpt
Associating genetic variants with phenotypes is not only important to understand the underlying biology but also to identify potential drug targets for treating diseases. It is widely accepted that for most complex traits many associations remain to be discovered, the so-called “missing heritability.” Yet missing heritability can be estimated, it is a known unknown, and we argue is only a fraction of the unknowns...
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Identifiers and source
- Literature Corpus work
- f9c662b2-1ff2-57f8-ab79-1d6e669f4985
- DOI
- 10.1101/553685