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Article

Genome-wide detection of intervals of genetic heterogeneity associated with complex traits.

Bioinformatics (Oxford, England) - 15 Jun 2015

Llinares-López Felipe, Grimm Dominik G, Bodenham Dean A, Gieraths Udo, Sugiyama Mahito, Rowan Beth, Borgwardt Karsten

Abstract excerpt

MOTIVATION: Genetic heterogeneity, the fact that several sequence variants give rise to the same phenotype, is a phenomenon that is of the utmost interest in the analysis of complex phenotypes. Current approaches for finding regions in the genome that exhibit genetic heterogeneity suffer from at least one of two shortcomings: (i) they require the definition of an exact interval in the genome that is to be tested...

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PMID: 26072488
DOI: 10.1093/bioinformatics/btv263
PMCID: PMC4559912

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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