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A Case of Pulmonary Langerhans Cell Sarcoma Simultaneously Diagnosed with Cutaneous Langerhans Cell Histiocytosis Studied by Whole-Exome Sequencing.

Acta haematologica - 1 Jan 2017

Kim Si-Wook, Choi Moon Ki, Han Hye Sook, Song Hyojin, Koh Youngil, Son Seung-Myoung, Lee Ok-Jun, Lee Ji Yeoun, Lee Ki Man, Lee Ki Hyeong, Kwon Jihyun

Abstract excerpt

Langerhans cell histiocytosis (LCH) and Langerhans cell sarcoma (LCS) are clonal proliferations of Langerhans-type cells. Unlike in LCH, the pathophysiology and clinical course of LCS are unclear due to its rarity. Here, we report the case of a 73-year-old male patient who was diagnosed with cutaneous LCH and pulmonary LCS at the same time. Pathological review of these 2 tumors revealed similar...

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Share to High-Throughput Nucleotide Sequencing
Share to Histiocytosis, Langerhans-Cell

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immunohistochemistry

Share to Mutation, Missense

Share to Positron-Emission Tomography

Share to Proto-Oncogene Proteins B-raf

Share to Tomography, X-Ray Computed

Share to Tumor Suppressor Protein p53

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Identifiers

PMID: 28614815
DOI: 10.1159/000476026

Genes

BRAF

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