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Article

Distinct genomic landscape of Chinese pediatric acute myeloid leukemia impacts clinical risk classification.

Nature communications - 28 Mar 2022

Liu Ting, Rao Jianan, Hu Wenting, Cui Bowen, Cai Jiaoyang, Liu Yuhan, Sun Huiying, Chen Xiaoxiao, Tang Yanjing, Chen Jing, Wang Xiang, Wang Han, Qian Wubin, Mao Binchen, Guo Sheng, Wang Ronghua, Liu Yu, Shen Shuhong

Abstract excerpt

Studies have revealed key genomic aberrations in pediatric acute myeloid leukemia (AML) based on Western populations. It is unknown to what extent the current genomic findings represent populations with different ethnic backgrounds. Here we present the genomic landscape of driver alterations of Chinese pediatric AML and discover previously undescribed genomic aberrations, including the XPO1-TNRC18 fusion....

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Identifiers

PMID: 35347147
DOI: 10.1038/s41467-022-29336-y
PMCID: PMC8960760

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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