Article

Evidence for functional and non-functional classes of peptides translated from long non-coding RNAs

2016-07-20

Abstract excerpt

There is accumulating evidence that some genes have originated de novo from previously non-coding genomic sequences. However, the processes underlying de novo gene birth are still enigmatic. In particular, the appearance of a new functional protein seems highly improbable unless there is already a pool of neutrally evolving peptides that can at some point acquire new functions. Here we show for the first time th...

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Literature Corpus work: 4d80d8f3-25b5-5209-8eb4-a83becd8ae37
DOI: 10.1101/064915

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