Article
De novo origin of protein-coding genes in murine rodents.
PloS one - 1 Jan 2012
Murphy Daniel N, McLysaght Aoife
Abstract excerpt
BACKGROUND: New genes in eukaryotes are created through a variety of different mechanisms. De novo origin from non-coding DNA is a mechanism that has recently gained attention. So far, de novo genes have been described in a handful of organisms, with Drosophila being the most extensively studied. We searched for genes that have appeared de novo in the mouse and rat lineages. METHODOLOGY: Using a rigorous and...
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