Article

In vitro models to mimic tumor endothelial cell-mediated immune cell reprogramming in lung adenocarcinoma

2024-10-15

Abstract excerpt

Tumor endothelial (TECs) cells play a critical role in regulating immune responses within the tumor microenvironment (TME). However, the mechanisms by which TECs modulate immune cell population remain unclear, particularly in non-small cell lung cancer (NSCLC). Here, we investigated how NSCLC cells tweak normal endothelial cells (NECs) into TECs and the subsequent effects on immune regulation. NECs were cocultured...

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Literature Corpus work: 4d7f69ec-d089-5acb-a1fa-1bc36ce67651
DOI: 10.1101/2024.10.13.618092

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