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Unveiling the immunomodulatory dance: endothelial cells’ function and their role in non-small cell lung cancer

16 Jan 2025

Abstract excerpt

The dynamic interactions between tumor endothelial cells (TECs) and the immune microenvironment play a critical role in the progression of non-small cell lung cancer (NSCLC). In general, endothelial cells exhibit diverse immunomodulatory properties, influencing immune cell recruitment, antigen presentation, and regulation of immune checkpoint expression. Understanding the multifaceted roles of TECs as well as...

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PMID: 39819502
DOI: 10.1186/s12943-024-02221-6

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