Article
Complex seizure disorder caused by Brunol4 deficiency in mice.
PLoS genetics - 1 Jul 2007
Yang Yan, Mahaffey Connie L, Bérubé Nathalie, Maddatu Terry P, Cox Gregory A, Frankel Wayne N
Abstract excerpt
Idiopathic epilepsy is a common human disorder with a strong genetic component, usually exhibiting complex inheritance. We describe a new mouse mutation in C57BL/6J mice, called frequent-flyer (Ff), in which disruption of the gene encoding RNA-binding protein Bruno-like 4 (Brunol4) leads to limbi...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.