Article

Development of an Antiseizure Drug Screening Platform for Dravet Syndrome at the NINDS contract site for the Epilepsy Therapy Screening Program

2020-12-02

Abstract excerpt

<h4>Summary</h4> <h4>Objective</h4> Dravet syndrome (DS) is a rare, but catastrophic genetic epilepsy, with 80% of patients with carrying a mutation in the SCN1A gene. Currently, no anti-seizure drug (ASD) exists that adequately controls seizures. Patients with DS often present clinically with a febrile seizure and generalized tonic-clonic seizures that continue throughout life. To facilitate the development of...

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Literature Corpus work: 89df99a1-b105-5381-8a96-fa482158a793
DOI: 10.1101/2020.12.01.406470

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