Article

DRIMSeq: a Dirichlet-multinomial framework for multivariate count outcomes in genomics

2016-12-06

Abstract excerpt

There are many instances in genomics data analyses where measurements are made on a multivariate response. For example, alternative splicing can lead to multiple expressed isoforms from the same primary transcript. There are situations where differences (e.g. between normal and disease state) in the relative ratio of expressed isoforms may have significant phenotypic consequences or lead to prognostic capabilities...

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Literature Corpus work: 45b3137a-0470-5e8e-8b76-aee7fe26e890
DOI: 10.12688/f1000research.8900.2

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