Article

Studying Antitumor Effect of Sirna Gene Silencing of Hif-1α, Pfkfb4 and Pdk1 in Glioblastoma Cell LINE

2026-05-25

Abstract excerpt

<title>Abstract</title> <p>Advances in early diagnosis and therapeutic strategies have improved cancer survival rates over recent decades. However, glioblastoma remains one of the most aggressive and treatment-resistant malignancies. Cancer cell metabolism, particularly glycolysis and the pentose phosphate pathway, plays a pivotal role in tumor growth and survival under hypoxic and nutrient-deprived conditions. T...

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Literature Corpus work: 4d7181ee-d3cf-53e0-8e1d-37b704625783
DOI: 10.21203/rs.3.rs-8839534/v1

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