Article

PGK1 promotes NSCLC progression by enhancing aerobic glycolysis and activating the AKT/ERK signaling pathway

2025-10-15

Abstract excerpt

<title>Abstract</title> <p> <bold>Backgrounds</bold> : Metabolic reprogramming, especially aerobic glycolysis, is considered a hallmark of cancer and is becoming a novel target for cancer therapy. Phosphoglycerate kinase I (PGK1), an important enzyme that generates the first ATP in the glycolysis pathway, has already shown aberrant expression in various cancers. <bold>Methods</bold> : After analyzing the pati...

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Literature Corpus work: 41ef1a7d-4c6a-579d-a347-abb27488905f
DOI: 10.21203/rs.3.rs-7433808/v1

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