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Article

Innate immunity in Caenorhabditis elegans is regulated by neurons expressing NPR-1/GPCR.

Science (New York, N.Y.) - 17 Oct 2008

Styer Katie L, Singh Varsha, Macosko Evan, Steele Sarah E, Bargmann Cornelia I, Aballay Alejandro

Abstract excerpt

A large body of evidence indicates that metazoan innate immunity is regulated by the nervous system, but the mechanisms involved in the process and the biological importance of such control remain unclear. We show that a neural circuit involving npr-1, which encodes a G protein-coupled receptor (...

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Identifiers

PMID: 18801967
DOI: 10.1126/science.1163673
PMCID: PMC2831475

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18801967-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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