Article

Stem cell-derived mouse embryos develop within an extra-embryonic yolk sac to form anterior brain regions and a beating heart

2022-08-02

Abstract excerpt

Embryo-like structures generated from stem cells can achieve varying developmental milestones, but none have been shown to progress through gastrulation, neurulation, and organogenesis. 1–7 Here, we show that “ETiX” mouse embryos, established from embryonic stem cells aggregated with trophoblast stem cells and inducible extraembryonic endoderm stem cells, can develop through gastrulation and beyond to undertake n...

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Literature Corpus work: 4d36de4a-909d-5e89-b472-5dbf67c24dc9
DOI: 10.1101/2022.08.01.502375

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Stem cell-derived mouse embryos develop within an extra-embryonic yolk sac to form anterior brain regions and a beating heartDOI 10.1101/2022.08.01.502375Read

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