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Dissecting peri-implantation development using cultured human embryos and embryo-like assembloids

17 Jul 2023

Abstract excerpt

Studies of cultured embryos have provided insights into human peri-implantation development. However, detailed knowledge of peri-implantation lineage development as well as underlying mechanisms remains obscure. Using 3D-cultured human embryos, herein we report a complete cell atlas of the early post-implantation lineages and decipher cellular composition and gene signatures of the epiblast and hypoblast...

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PMID: 37460804
DOI: 10.1038/s41422-023-00846-8

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