Article

Robust self-organization of livestock pluripotent stem cells into post-gastrulation embryo models with advanced neuronal and mesodermal structures

2026-03-04

Abstract excerpt

Mammalian body plan formation arises from the self-organization of pluripotent cells through conserved morphogenetic processes that are difficult to study in vivo. Stem cell–based embryo models (SEMs) offer accessible three-dimensional systems to investigate these events but are currently limited to mouse and human cells and largely recapitulate posterior embryonic structures. In addition, no in-vitro models exist...

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Literature Corpus work: eec91a2a-d853-53f9-a2bc-c36cd3ee088c
DOI: 10.64898/2026.03.02.709113

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