Article

Dissecting peri-implantation development using cultured human embryos and embryo-like assembloids

2023-06-16

Abstract excerpt

Studies of cultured embryos have provided insights into human peri-implantation development. However, detailed knowledge of peri-implantation lineage developments as well as underlying mechanisms remain obscure. Using 3D-cultured human embryos, herein we report a complete cell atlas of the early post-implantation lineages and decipher cellular composition and gene signatures of the epiblast and hypoblast derivativ...

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Literature Corpus work: e2eb01f2-207f-597f-ae12-870d0b8547e3
DOI: 10.1101/2023.06.15.545180

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