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Article

Chikungunya virus neutralization antigens and direct cell-to-cell transmission are revealed by human antibody-escape mutants.

PLoS pathogens - 1 Dec 2011

Lee Chia Yin, Kam Yiu-Wing, Fric Jan, Malleret Benoit, Koh Esther G L, Prakash Celine, Huang Wen, Lee Wendy W L, Lin Cui, Lin Raymond T P, Renia Laurent, Wang Cheng-I, Ng Lisa F P, Warter Lucile

Abstract excerpt

Chikungunya virus (CHIKV) is an alphavirus responsible for numerous epidemics throughout Africa and Asia, causing infectious arthritis and reportedly linked with fatal infections in newborns and elderly. Previous studies in animal models indicate that humoral immunity can protect against CHIKV infection, but despite the potential efficacy of B-cell-driven intervention strategies, there are no virus-specific...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22144891
DOI: 10.1371/journal.ppat.1002390
PMCID: PMC3228792

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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