Article

Identification of immunogenic and cross-reactive chikungunya virus-specific CD4 <sup>+</sup> T cell epitopes in chronic chikungunya viral arthritic disease in humans

2024-10-25

Abstract excerpt

<h4>ABSTRACT</h4> Chikungunya virus (CHIKV), a mosquito-borne alphavirus, causes acute febrile illness that can progress into chronic chikungunya virus disease (CHIKVD) marked by persistent debilitating arthralgia. At present, the exact cause of chronic CHIKVD is not understood, and in humans, the targets of CD4 + T cells in CHIKV are currently unknown. Here, by stimulating peripheral blood mononuclear cells (PB...

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Literature Corpus work: e3f91ad5-aed1-572a-80f7-95d3fa921209
DOI: 10.1101/2024.10.22.619717

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