Article
Evolution and immunopathology of chikungunya virus informs therapeutic development.
Disease models & mechanisms - 1 Apr 2023
Henderson Sousa Filipa, Ghaisani Komarudin Amalina, Findlay-Greene Fern, Bowolaksono Anom, Sasmono R Tedjo, Stevens Craig, Barlow Peter G
Abstract excerpt
Chikungunya virus (CHIKV), a mosquito-borne alphavirus, is an emerging global threat identified in more than 60 countries across continents. The risk of CHIKV transmission is rising due to increased global interactions, year-round presence of mosquito vectors, and the ability of CHIKV to produce high host viral loads and undergo mutation. Although CHIKV disease is rarely fatal, it can progress to a chronic stage,...
Topics
- Animals
- Humans
- Chikungunya virus
- Mosquito Vectors
- Chikungunya Fever
- Antiviral Agents
- Mutation