Article

The <i>C. elegans</i> Myc-family of transcription factors coordinate a dynamic adaptive response to dietary restriction

2023-11-22

Abstract excerpt

Dietary restriction (DR), the process of decreasing overall food consumption over an extended period of time, has been shown to increase longevity across evolutionarily diverse species and delay the onset of age-associated diseases in humans. In Caenorhabditis elegans , the Myc-family transcription factors (TFs) MXL-2 (Mlx) and MML-1 (MondoA/ChREBP), which function as obligate heterodimers, and PHA-4 (orthologous...

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Literature Corpus work: 4cf94629-bb82-5686-a013-a0037204229d
DOI: 10.1101/2023.11.22.568222

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